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Benjamin L Makepeace Selected Research

Intestinal Volvulus (Volvulus)

7/2023Adjuvanted Fusion Protein Vaccine Induces Durable Immunity to Onchocerca volvulus in Mice and Non-Human Primates.
5/2022Co-Administration of Adjuvanted Recombinant Ov-103 and Ov-RAL-2 Vaccines Confer Protection against Natural Challenge in A Bovine Onchocerca ochengi Infection Model of Human Onchocerciasis.
11/2021Development of a recombinant vaccine against human onchocerciasis.
1/2021Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice.
1/2016Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle.
1/2015Extracellular Onchocerca-derived small RNAs in host nodules and blood.
1/2014A simple isothermal DNA amplification method to screen black flies for Onchocerca volvulus infection.
1/2014Efficacy of three-week oxytetracycline or rifampin monotherapy compared with a combination regimen against the filarial nematode Onchocerca ochengi.
11/2009Immunisation with a multivalent, subunit vaccine reduces patent infection in a natural bovine model of onchocerciasis during intense field exposure.
6/2008UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.

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Benjamin L Makepeace Research Topics

Disease

15Onchocerciasis
05/2022 - 10/2005
11Infections
05/2022 - 03/2005
10Intestinal Volvulus (Volvulus)
07/2023 - 06/2008
8Ocular Onchocerciasis (River Blindness)
01/2021 - 01/2007
1Hypertrophy
05/2024
1Lyme Disease (Disease, Lyme)
01/2023
1Relapsing Fever
01/2023
1Scrub Typhus (Typhus, Scrub)
09/2022
1Neglected Diseases
01/2021
1Vision Disorders (Hemeralopia)
08/2015
1Eosinophilia
08/2015
1Pruritus (Itching)
08/2015
1Loiasis
01/2015
1Filariasis
10/2014
1Lymphatic Diseases
10/2014
1Reinfection
01/2007
1Meningitis
03/2005
1Meningococcal Meningitis
03/2005
1Blister (Bulla)
03/2005
1Meningioma (Meningiomas)
08/2002

Drug/Important Bio-Agent (IBA)

9VaccinesIBA
07/2023 - 10/2014
7Ivermectin (Mectizan)FDA Link
01/2021 - 01/2007
3Biomarkers (Surrogate Marker)IBA
12/2017 - 01/2015
3Anti-Bacterial Agents (Antibiotics)IBA
08/2015 - 10/2005
2Proteins (Proteins, Gene)FDA Link
07/2023 - 08/2002
2AntigensIBA
07/2023 - 11/2021
2Palm OilIBA
01/2023 - 09/2022
2Synthetic Vaccines (Recombinant Vaccines)IBA
05/2022 - 11/2021
2emodepsideIBA
01/2021 - 01/2021
2AnthelminticsIBA
01/2021 - 01/2021
2Glutathione Transferase (Glutathione S-Transferase)IBA
12/2019 - 01/2014
2Oxytetracycline (Terramycin)FDA Link
01/2007 - 10/2005
2CytokinesIBA
03/2005 - 08/2002
1RNA (Ribonucleic Acid)IBA
05/2024
1delta inulinIBA
07/2023
1aluminum sulfate (alum)IBA
07/2023
1EnzymesIBA
12/2019
1O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfateIBA
12/2019
1XenobioticsIBA
12/2019
1ProteomeIBA
01/2016
1Tetracycline (Achromycin)FDA LinkGeneric
08/2015
1MicroRNAs (MicroRNA)IBA
01/2015
1Adenosine Triphosphate (ATP)IBA
10/2014
1IronIBA
10/2014
1Heme (Haem)IBA
10/2014
1DNA (Deoxyribonucleic Acid)IBA
01/2014
1AntibodiesIBA
11/2009
1Recombinant ProteinsIBA
11/2009
1Subunit VaccinesIBA
11/2009
1melarsomineIBA
04/2006
1TetracyclinesIBA
10/2005
1Pattern Recognition ReceptorsIBA
03/2005
1LipopolysaccharidesIBA
03/2005
1Interleukin-6 (Interleukin 6)IBA
08/2002
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2002
1CXC ChemokinesIBA
08/2002
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
08/2002
1Interleukin-8 (Interleukin 8)IBA
08/2002
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2002
1Chemokine CCL5IBA
08/2002
1CC ChemokinesIBA
08/2002

Therapy/Procedure

5Mass Drug Administration
11/2021 - 01/2014
3Drug Therapy (Chemotherapy)
01/2014 - 10/2005
1Contraindications
01/2015
1Aftercare (After-Treatment)
03/2005